Kiticharoensak Ornrapee Author

Conference Proceeding Open Access

A Review of the Efficacy and Safety of Retinoids in the Treatment of Ultraviolet Related Skin Conditions and Skin Ageing

Author(s):

Kiticharoensak Ornrapee

Retinoids refer to all natural and synthetic products having a structure or biological activities similar to vitamin A, which helps to modulate the function of homeostasis, metabolism, epithelial growth and immune regulation as well as inflammation via retinoid receptors. Recently, there has been a growing interest in retinoids in the management of UV-related skin conditions, including skin cancer, solar ageing as well as dyspigmentation, which cause a huge dermatological and psychological burden on patients. However, scientific evidence and a standard guideline of retinoids on these conditions are still limited. Skin cancer is caused by accumulative DNA damage by UVR along with an impaired DNA repair mechanisms. Retinoids seem to have a chemopreventive effect by modulating the repair p... view more»

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