Kumar A Author
Subjects of specialization
Affiliation
Pharmacology , Sleep Medicine
Department of Pharmacology, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Study, Punjab University, India
Pharmacology Division, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Study, Pa njab University, India.
He recently published his articles in Journal of Sleep Disorders: Treatment and Care. He reviewed many scientific papers. His research interests reflect in his wide range of publications in various national and international journals.
Research Article Subscription
Author(s): Chanana P and Kumar A
Introduction: Sleep deprivation [SD] often raises several neurological problems by causing significant alterations at multiple neural systems. Centella asiatica is a psychoactive medicinal herb with immense therapeutic potential.
Objective: The present study has been designed with aim to target mitoprotective and anti-stress pathways involved in the protective effect of Centella asiatica in addition to nitric oxide mechanism.
Methods: Male laca mice were sleep deprived for 72 hours using grid suspended over water method and Centella asiatica (150 and 300mg/kg) was administered alone and in combination with NO modulators for 8 days, starting five days before 72 hours sleep deprivation. Various behavioural (pen... view moreĀ»