Kurt Farrell Author
Subjects of specialization
Affiliation
Biomedical Research, Neuroscience, Pathology, Stem Cells
Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, US
Kurt W Farrell have an Research Experience at Cleveland State University in Department of Chemical and Biomedical Engineering and Icahn School of Medicine at Mount Sinai in Department of Pathology United States. Member Directory in AlzForum Networking for a cure.
Review Article Subscription
Author(s): Kurt Farrell and Chandrasekhar R. Kothapalli
Tissue Engineering Approaches for Motor Neuron Pathway Regeneration
During fetal development, a tightly-regulated spatio-temporal pattern of guidance cues directs and maintains motor neuron axonal growth along specific pathways to reach the target cells and tissues. However, an inflammatory environment resulting from an injury (e.g., trauma, stroke) or disease [e.g., amyotrophic lateral sclerosis (ALS), primary lateral sclerosis (PLS), and hereditary spastic paraplegia (HSP)] leads to progressive degeneration of motor neurons and destruction of axonal tracts in the adult CNS.
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