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Hindi Journal of Virology & Antiviral ResearchISSN: 2324-8955
Kwofie Theophilus Benjamin Author
Subjects of specialization
Affiliation
Chimeric Viruses, Cytokines, Chemokines
epartment of Clinical Microbiology, School of Medical Sciences, College Health Science, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
Biography
Dr. Theophilus Benjamin Kwofie is a Senior Lecturer at the Department of Clinical Microbiology of the School of Medical Sciences (SMS) KNUST, Kumasi, Ghana. He holds a MSc. Degree in Molecular Biology (Kyorin University) and a PhD degree in Virology (Kyoto University), both universities in Japan. Prior to this he worked with the Noguchi Memorial Institute for Medical Research, Legon in Accra from 1980 to 1992 as a laboratory Technician.
Publications
Research Article Subscription
Enhanced Fitness of Non-Pathogenic SHIV-NM-3rN Over Acute Pathogenic 89.6P in a Dual Infection/Compitition Assay on HSC-F Monkey Derived Cell Line
Author(s): Kwofie Theophilus Benjamin and Miura Tomoyuki
Enhanced Fitness of Non-Pathogenic SHIV-NM-3rN Over Acute Pathogenic 89.6P in a Dual Infection/Compitition Assay on HSC-F Monkey Derived Cell Line
In a study to use a non-pathogenic Simian/Human Immunodeficiency Virus (SHIV) to overcome pathogenic SHIV in a dual infection/competition assay, two SHIVs, pathogenic 89.6P and non-pathogenic NM-3rN, whose replicative fitness were adjusted to be of equal strength, were mixed together and allowed to compete during many transfers in a monkey-derived cell line HSC-F. This is to identify the conditions under which a nonpathogenic SHIV could out-compete a pathogenic SHIV in order to understand the principles underlying evolution of ... view more»
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