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Hindi Journal of Aging and Geriatric MedicineISSN: 2576-3946
Labunets IF Author
Subjects of specialization
Affiliation
Multipotent mesenchymal stromal cells; Biological properties; Bonemarrow; Age
Cell and Tissue Technology Department, State Institute of Genetic and Regenerative Medicine, National Academy of Medical Sciences of Ukraine, Ukraine
Biography
| Labunets IF Cell and Tissue Technology Department, State Institute of Genetic and Regenerative Medicine, National Academy of Medical Sciences of Ukraine, Ukraine |
Publications
Research Article Open Access
Age Dependent Changes of Biological Properties in the Multipotent Mesenchymal Stromal Bone Marrow Cells in FVB Mice
Author(s): Rodnichenko AE, Labunets IF and Utko NA
Objective: In the last years researchers’ attention has been given to the immunomodulatory properties of multipotent mesenchymal stromal cells. The question of effectiveness of the stem cell therapy with MSCs from elderly donors is worth studying. Our aim was to compare the potency of bone marrow MSCs in aging.
Methods: BM-MSCs were obtained using the standard methods. The following methods were applied: immunophenotyping, colony-forming unit fibroblast assay, granulocyte/macrophage colony-forming cells assay in the semi-agar cultures, directed differentiation, colorimetric method, MTT assay.
Results: The stromal progenitor cells... view more»
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