Journal of Diagnostic Techniques and Biomedical AnalysisISSN: 2469-5653

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Lauren Gorelick Author

Subjects of specialization
Trapeziometacarpal joint osteoarthritis; Interposition arthroplasty; Polylactic acid implant; Foreign body giant cells; Polylactic acid implant degradation

Affiliation
Hand Surgeon, Assuta Medical Center, Haifa, Israel

Biography

Lauren Gorelick Hand Surgeon, Assuta Medical Center, Haifa, Israel                                                                                                                                         


Publications

Case Report Subscription

Local Tissue Damage as a Possible Trigger to Giant Cell’s Inflammatory Response and Failure Following Trapezectomy and Interposition of Polylactic Acid Arex Trapezium Implant: A Case Report.

Author(s):

Lauren Gorelick, Ayala Rozano-Gorelick, Anwar Saab, Edward Ram

Local Tissue Damage as a Possible Trigger to Giant Cell’s Inflammatory Response and Failure Following Trapezectomy and Interposition of Polylactic Acid Arex Trapezium Implant: A Case Report.

Polylactic acid (PLA) braid rolled on itself AREX trapezium implant is a part of surgical treatment in patients with Eaton type III-IV of trapeziometacarpal joint (TM) osteoarthritis. The foreign body reaction composed of macrophages and foreign body giant cells is the end-stage of the inflammatory responses following implantation of the PLA prosthesis. Prolonged resorptive giant cells immune inflammatory response, leading the patients to undergo revision surgery for removal of the implant before the end of the third p... view more»

DOI: 10.4172/2469-5653.1000109

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