Mackenzie Cottrell Author
Subjects of specialization
Affiliation
Pharmacokinetic, Pharmacotherapy, Pharmacodynamic
Department of Experiential Education, University of Oklahoma College of Pharmacy, Oklahoma City, Oklahoma 73117, USA
Mackenzie Cottrell is an assistant professor in the Division of Pharmacotherapy and Experimental Therapeutics. Her research focuses on describing pharmacokinetic/pharmacodynamic relationships in mucosal tissues for antiretrovirals being used in prevention and cure interventions.
Research Article Subscription
Author(s): Mackenzie Cottrell, R Chris Rathbun, Ryan Webb, Pete Johnson and Staci M Lockhart
Implications for Hepatitis C Treatment and Disease Progression in an HIV/HCV Co-Infected Population
Morbidity and mortality rates from chronic liver disease secondary to hepatitis C virus (HCV) have become a significant issue for HIV infected patients. U.S. Department of Health and Human Service guidelines recommend HCV treatment for all coinfected patients without decompensated liver disease. Telaprevir and boceprevir are direct-acting agents (DAAs) recently approved for HCV genotype-1 mono-infection and have demonstrated marked improvements in viral suppression when combined with peg-interferon/ribavirin as triple therapy. Identification of co-infected patients who coul... view moreĀ»