Mairin A. Jerome3 Author
Subjects of specialization
Affiliation
Cellular Immunology,Cellular Pathology,Cell Regeneration,Cell Regeneration,Cell Motility
Associate Professor, Department of University College
He has international experience on various programs, and also contributed and participated in different countries for diverse fields of study. Research interests reflect in wide range of publications in various national and international journals.
Short Communication Open Access
Author(s): Kenneth Mautner1,2, Mairin A. Jerome3 , Kirk Easley4 , Katherine Nanos5 , Peter A. Everts6
Mesenchymal Stem Cells (MSCs) from Bone Marrow Concentrate (BMC) have emerged as a promising treatment for degenerative musculoskeletal pathologies, such as Osteoarthritis (OA). Many aspiration techniques have been described in the literature with little consensus on optimal methodology. This study aimed to compare MSC quantity in unilateral versus bilateral Posterior Superior Iliac Spine (PSIS) bone marrow aspirate concentrations. Patients with unilateral knee OA seeking treatment with intraarticular BMC were recruited and randomized to a unilateral PSIS Bone Marrow Aspiration (BMA) or a bilateral PSIS BMA of equal total volumes. BMA and BMC samples underwent laboratory analysis of Colony Forming Unit-Fibroblasts (CFU-fs) as a marker for MSCs, for quantification of Total Nucleated Cell... view moreĀ»