Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi Endocrinology & Diabetes ResearchISSN: 2470-7570
Manisha Chandalia Author
Subjects of specialization
Affiliation
working in the Department of Veteran Affairs Medical Center (M.C., S.M.G., A.G.), Dallas, Texas 75235,(M.C., S.M.G., A.G.), Dallas, Texas 75235
the Department of Internal Medicine (M.C., N.A., S.M.G., A.G.), University of Texas Southwestern Medical Center, Dallas, Texas 75235
Biography
It has been proposed that excessive insulin resistance in Asian Indians living in urban areas the Department of Internal Medicine (M.C., N.A., S.M.G., A.G.), University of Texas Southwestern Medical Center, Dallas, Texas 75235
Publications
Editorial Subscription
New Insights into the Role of ENPP1 in Insulin Resistance
Author(s): Wentong Pan, Manisha Chandalia and Nicola Abate
New Insights into the Role of ENPP1 in Insulin Resistance
Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) is a transmembrane glycoprotein highly expressed in adipocytes and also found in other tissues involved in glucose and lipid metabolism, including liver, skeletal muscle and beta cell of the pancreas. Early studies demonstrated that ENPP1 interacts with the insulin receptor at the level of the alpha subunit. This interaction results in decreased insulin-mediated activation of the tyrosine phosphorylation in the beta-subunit of the insulin receptor, and downstream insulin signaling activation.
... view more»Social Media
Google Scholars / Researchers Sites
