Marcelo Henrique Prado da Silva1 Author

Review Article Open Access

Mesenchymal Stem Cells Associated with Bioceramics for Bone Tissue Regeneration

Author(s):

Daniel Navarro da Rocha, Rubens Lincoln Santana Blazutti Marçal, Rafael Maza Barbosa, José Ricardo Muniz Ferreira, Marcelo Henrique Prado da Silva1*

Bioactive bioceramics are a family of osteoconductive materials that include bioactive glass and calcium phosphates such as hydroxyapatite (HA) and tricalcium phosphate (β-TCP or α-TCP). These materials exhibit excellent bone binding properties and are usually designed to be used as bone fillers or as bioactive coatings on metal implants. Their in vivo resorption ability may be modulated by controlling synthesis and processing parameters. Bioceramics can be associated to stem cells in cell-based therapies, using transplanted cells to guide the spatially complex process of tissue formation, thus optimizing osteoinduction, osteoconduction, and osteogenesis. Although tissue engineering strategies using stem cells aim to ameliorate the prognosis ... view more»

DOI: 10.4172/2577-0268.1000110

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