Research and Reports in Gastroenterology

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Marta Chiavetta Author

Subjects of specialization
Toxic Megacolon, Clostridium difficile colitis, Inflammatory Bowel Diseases

Affiliation
Department of Internal Medicine, University of Palermo, Palermo, Italy

Biography

Myself Marta Chiavetta , I belong to Department of Interl Medicine, University of Palermo, Palermo, Italy


Publications

Review Article Open Access

Toxic Megacolon: Management Challenges

Author(s):

Stella Compagnoni, Marta Chiavetta and Mario Cottone 

Toxic Megacolon (TM) is a non-obstructive dilatation of the colon, either total or segmental, associated with systemic toxicity. Even though it is best known as a consequence of Inflammatory Bowel Diseases (IBD) and it is mostly related to Ulcerative Colitis (UC), it may be also a complication of other conditions, such as infectious diseases. In fact, the epidemiology of TM has lately changed: there has been a recent increase in the number of reports of TM associated with pseudomembranous colitis (PMC) and, hereupon, the Clostridium difficile has spread as one of the most important causes of TM. However, more precise data about the epidemiology of TM should be collected. Due to its systemic involvement, TM is a severe and life-threatening condition that still represents a big challenge ... view moreĀ»

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