Marwa K. Darwish Author

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Role of Interleukin-10, Interleukin-12 in the Response Prediction during Combined PEG Interferon-alpha 2a and Ribavirin Therapy in Patients with Chronic Hepatitis C

Author(s):

Amal Ahmed Mohamed*, Marwa M E Abd Elmonsef, Marwa K. Darwish , Mohamed A Atallah, Mohamed Ezz, Said El-Feky and Heba Ebrahim

Background: Egypt has the highest prevalence of adult HCV infection in the world, averaging 15%-25% in rural communities. Sustained virological response in genotype 4 Egyptian patients treated with PEG-IFN alfa-2a and ribavirin was estimated around 60%. It is of major interest for both patient care and economic approach to predict failure of response. Several factors have been shown to influence response to antiviral treatment. Cytokines play an important role in the pathogenesis, progression and treatment outcome of view more»

DOI: 10.4172/2324-8955.1000134

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