Masato Miwa Author
Subjects of specialization
Affiliation
arachidonic
Masato Miwa belonging to the department of imbalance of the peroxide tone
Masato Miwa belonging to the department of imbalance of the peroxide tone in the nasal mucosa caused by stimulation of the cyclooxygenase pathway of the arachidonic acid cascade and ROS formation was demonstrated. Moreover, the increased number of ROS was not well metabolized in the nasal mucosa with allergy.
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Author(s): Masato Miwa, Noritsugu Ono, Daisuke Sasaki, Akihito Shiozawa, Mayumi Miwa and Katsuhisa Ikeda
Peroxide Tone in Human Inferior Nasal Turbinate with Allergy
Background: The nose is chronically exposed to oxidative stress, which can easily lead to reactive oxygen species (ROS)-mediated damage and lipid oxidative damage of the upper airway. ROS may also participate in various diseases, including those of the airway, although many details are not yet known. ROS is generated by various enzymatic reactions and chemical processes. Superoxide dismutase (SOD), catalase, and glutathione peroxidase (GSH-Px) are representative scavengers. ROS are also generated through arachidonic acid cascades. One of the primary prostaglandins (PG), PGD2, is the major PG in most types of tiss... view moreĀ»