Journal of Clinical Images and Case Reports

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Mohamed Shirazy Author

mohamed_shirazy@yahoo.com

Subjects of specialization
chlorpheniramine, Procalcitonin(PCT), Anaphylaxis

Affiliation
Mohamed Shirazy Department of Emergency Medicine, Alexandria University, Egypt

Biography

Mohamed Shirazy is specialised in both ICU and Emergency Medicine. Completed his graduation from the Alexandria University, Egypt in 2008, he did his ICU training for 5 years during which he got a master degree in Critical Care Medicine. Completed his Diploma in Intensive Care Medicine and the Membership of the Royal College of Emergency Medicine and currently works as an associate specialist in Emergency Medicine in the University Hospitals of Morcambe Bay NHS, UK.

Publications

Special Issue Article Open Access

A Case of Oropharyngeal Angioedema Following Intravenous Recombinant Tissue Plasminogen Activator (rt‐PA) and Mechanical Thrombectomy

Author(s):

Mohamed Shirazy, Anis Chaari, Karim Hakim, Kamel Bousselmi, Vipin Kauts

 

A 72-year-old housewife presented with ischemic cerebrovascular stroke. Intravenous thrombolysis using recombinant tissue plasminogen activator (rt-PA) followed by mechanical thrombectomy under general anesthesia were attempted. The patient developed stridor and tongue swelling, in addition to hypotension and bradycardia, 60 min after completion of the rt-PA infusion. The airway was intubated, and intramuscular adrenaline, together with intravenous hydrocortisone and diphenhy- dramine, were administered. On the second day, the tongue edema subsided, and the cuff leak test was negative. However, extubation was not attempted due to the development of brain edema. A tracheostomy was later performed, and the patient was weaned off mechanical ventilation.
Biography:
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