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Hindi International Journal of Ophthalmic PathologyISSN: 2324-8599
Mohammed F Qutub Author
Subjects of specialization
Affiliation
Ocular pathology, Ophthalmology
Henry C Witelson Ocular Pathology Laboratory, 815 De la Commune East, H2L 0A4, Montreal, Quebec, Canada
Biography
Mohammed F Qutub currently completing a pre-residency research fellowship in ocular pathology at McGill University in Montreal, QC, Canada. My greatest passion lies in ophthalmology, and I enjoy engaging in research initiatives that further enhance the field and clinicians’ practices. I have a great desire to participate in critical research projects in ophthalmology in order to contribute to the scientific community, to improve patients’ quality of life, as well as to enhance my ever-evolving research skills and knowledge base
Publications
Research Article Subscription
Toll-Like Receptor 3 is Expressed in All Layers of the Human Sensory Retina and Retinal Pigment Epithelium
Author(s): Mohammed F Qutub, Pablo Zoroquiain, Shawn C Maloney, Sultan S Aldrees and Miguel Jr Burnier
Purpose: Recent studies have found that dysregulation of Toll-like receptor 3 (TLR3)-a key player in innate immunity-in retinal pigmented epithelium (RPE) may play a role in retinal oxidative stress. The aim of this study was to evaluate the expression of TLR3 in all layers of the normal human retina.
Methods: Formalin-fixed, paraffin-embedded sections of human donor eyes-with no fundoscopic or microscopic evidence of disease-were used in this study. Mean age of donors was 62.8 ± 31.5 years (12 female, 7 male). Immunohistochemistry was performed using an antibody to human TLR3 and staining was scored according to intensity (0=negative, 1=low-to-moderate, 2=strong) and extent (0=neg... view more»
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