Nafees Ahmad Author
Subjects of specialization
Affiliation
Immune response, Immunobiology, Biochemistry, Microbiology, Pharmacology
Department of Immunobiology, College of Medicine, University of Arizona, Tucson, Arizona , USA
Review Article Subscription
Author(s): Nafees Ahmad
HIV-1 exists as a genetically heterogeneous population within infected individuals and in infected population. Genetic variability or viral heterogeneity plays an important role in transmission, pathogenesis, immune response, disease progression and therapy as well as is the most effective way for the virus to evade the host immune response and persists in infected individuals. We have used HIV-1 infected motherinfant pairs as a transmitter-recipient model to elucidate the role of the molecular and biological properties of HIV-1 associated with transmission and pathogenesis. HIV-1 sequences derived from infected mothers were more heterogeneous than their younger ... view moreĀ»