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Hindi Journal of Clinical & Experimental OncologyISSN: 2324-9110
Nirushika Mohanaraja Author
Subjects of specialization
Affiliation
Mucoepidermoid carcinoma, Breast cancer, Prostate biomarker, Endometrial cancer
Department of Medical physics, Technical University Dortmund, Dortmund, Germany
Biography
Nirushika Mohanaraja was working in the Department of Medical physics, Technical University Dortmund, Dortmund, Germany. She has more than 40 publications. Her current research area related to osteoarthropathy
Publications
Research Article Subscription
Feasibility of Single Tumorspot Treatment in Peritoneal Carcinomatosis via Close Range Doxorubicin Impaction in Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC)
Author(s): Tanja Khosrawipour, Dan Wu, Alexander Bellendorf, Nirushika Mohanaraja, Ebru Karabay, David Diaz-Carballo and Veria Khosrawipour
Background: Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) is a well-established, yet not fully evaluated new treatment approach for peritoneal carcinomatosis with the aim at enabling localized application of chemo aerosol within the abdominal cavity. Distribution inhomogeneity in PIPAC has been previously indicated in prior experiments. This study was conducted to investigate whether this finding can be used to achieve localized high drug concentrations into micro metastasis.
Materials and Methods: PIPAC construct was built using a hermetic container system which mimics the abdominal cavity. Fresh parietal peritoneum portions from post-mortem swine were cut into samples and placed vertically in the center of a box. The Micropump©... view more»
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