Journal of Virology & Antiviral ResearchISSN: 2324-8955

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Pamela A. Norton Author

pamela.norton@drexelmed.edu

Subjects of specialization
Microbiology & Immunology, Chronic viral hepatitis, Molecular Medicine , Biomarker

Affiliation
Department of Microbiology & Immunology and Drexel Institute for Biotechnology & Virology Research, Drexel University College of Medicine, USA

Biography

Pamela Norton is an associate professor in the Department of Microbiology & Immunology at Drexel University College of Medicine. She is also co-director of the Molecular Medicine master's degree program.Her current research intrests include Characterization of glycoproteomic biomarkers for hepatocellular carcinoma, induction of novel immune responses by agents that alter N-glycan processing.

Publications

Editorial Open Access

Hepatitis B Virus Cellular Entrys Erecting a Barrier

Author(s):

Pamela A. Norton

Hepatitis B Virus Cellular Entry– Erecting a Barrier

The identity of the cell surface receptor (or receptors) that mediates infection of human hepatocytes by Hepatitis B virus (HBV) has proven elusive. A number of candidates have been proffered over the years, but the lack of good cell culture-based infectivity model systems has tended to frustrate researchers in the field. A recent report using the HepaRG human hepatoma cell line offers insights into cellular barriers to viral entry. The data suggest that the susceptible cells must adopt a polarized architecture similar to hepatocytes within the normal liver, including the formation of bile canalicu... view more»

DOI: 10.4172/2324-8955.1000e102

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