Paul Gruuml;ndeman Author

Research Article Open Access

In vitro Hemocompatibility Testing of Dyneema Purity® Fibers Patch and Clinically Used Cardiovascular Prostheses

Author(s):

Amir Basir*, Mark Roest, Mylène Loncq de Jong, Wally Müller, Joost van Herwaarden, Frans Moll, Gerard Pasterkamp, Jolanda Kluin, Paul Gründeman and Philip de Groot

Objectives
Currently available materials for vascular- and heart valve prostheses carry drawbacks, including the requirement of strong anticoagulants, moderate durability, and the inapplicability for endovascular treatment. Dyneema Purity® fibers are made from ultra-high molecular weight polyethylene, are very thin, strong, flexible and resistant to fatigue and abrasion. This material might be attractive for use in vascular- and valvular surgery. In this study the hemocompatibility of yarn-composed patches of Dyneema Purity® fibers was assessed.
Methods
Three methods were used to compare the hemocompatibility of yarn-composed patches of Dyneema Purity® fibers with 5 clinically used yarn-composed and
membrane-based patches. First, patches were perfused wit... view more»

Abstract HTML PDF