Ping Li | Author | SciTechnol | Endocrinology & Diabetes Researc

Ping Li Author

PingLi@gmail.com

Subjects of specialization
transient receptor

Affiliation
China-Japan Friendship Hospital, China .

Biography

Ping Li is the chairman of Beijing Key Lab for ImmuneMediated Inflammatory Diseases, Institute of Clinical Medical Science, China-Japan Friendship Hospital. She has engaged in the clinical and basic research of integrated traditional Chinese

Publications

Annual Meeting Abstract Open Access

Role of transient receptor potential canonical channel 6 (TRPC6) in diabetic kidney disease by regulating podocyte actin cytoskeleton rearrangement

Author(s):

Ping Li

Podocyte injury is an important pathogenesis step causing proteinuric kidney diseases such as diabetic kidney disease (DKD). Actin cytoskeleton rearrangement in podocyte induced by multiple pathogenic factors is believed the key process resulting into its injury. Many studies have recently shown that transient receptor potential canonical channel 6 (TRPC6) in podocyte plays a critical role in the development and progression of proteinuric kidney disease, that participate in proteinuria formation by regulating its actin cytoskeleton rearrangement. This review aims to summarize the TRPC6 role in podocyte on DKD by regulating the actin cytoskeleton rearrangement, thereby help further broaden our views and understanding on the mechanism of DKD and provide a theoretic basis for exploring new... view more»

Abstract PDF