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Hindi Endocrinology & Diabetes ResearchISSN: 2470-7570
Qiang Jiang Author
Subjects of specialization
Affiliation
Science Cente, Resources, Remote Sensin
Earth Resources Observation and Science Center, Hefei University of Technology, Institute of Remote Sensing Application Chinese Academy of Sciences, University of North Dakota
Biography
Hamamatsu Ika Daigaku, The Jikei University Hospital, Tokyo Dental College Ichikawa General Hospital, University of Western States, Wake Forest University
| Hamamatsu Ika Daigaku, The Jikei University Hospital, Tokyo Dental College Ichikawa General Hospital, University of Western States, Wake Forest University |
Publications
Short Communication Open Access
Metformin Influences Bile Acids to Improve the Glucose and Lipid Metabolism in Rats with Streptozotocin-induced Type 2 Diabetes Mellitus
Author(s): Jianting Li, Yang Liu, Qiang Jiang, Lulu Wang, Rui Shi, Xiaoxia Ma, Lin Ding and Shuguang Pang
The prevalence of type 2 diabetes mellitus (T2DM), which is characterized by an increased blood glucose concentration, insulin resistance and pancreatic beta-cell dysfunction has reached epidemic proportions worldwide and represents an important threat to global public health systems [1]. On the basis of available clinical evidence, metformin has been affirmed as the first-line therapy for patients with T2DM [2]. Although a few pathophysiological mechanisms have been proposed to explain these beneficial clinical effects of metformin, detailed mechanisms of action of metformin are still not fully understood, especially its relationship with bile acids.
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