Research Journal of Clinical Pediatrics

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Raktima Chakrabarti Author

chakrabarti@gmail.com

Subjects of specialization
General Pediatrics, Neonatology, Development Pediatrics and Neuropsychology, Pediatri Critical Care, Adolescent Medicine

Affiliation
Department of Mother and Child, Faculty of Medicine, University of Parakou, PO Box 123, Parakou, Benin

Biography

I have done my sub-speciality training in Paediatric Respiratory Medicine. Pediatric Nephrology at the University of Tennessee, where he founded the pediatric General Clinical Research Center.

Publications

Special Issue Article Open Access

Necrotizing Enterocolitis- An Analysis of Recent Development

Author(s):

Raktima Chakrabarti

Necrotizing Enterocolitis (NEC) is a dreaded gastrointestinal disease in neonates, mainly preterm neonates. It needs multipronged approach for the treatment and prevention. The first case was reported in 1823. But till now there is hardly any definite treatment in advanced stages, and prevention has the main role.

In NEC, the intestinal mucosa actually dies, becomes totally necrosed soggy and dies off. What is the actual cause of this death and why it is more prevalent in preterm, is not fully clear. Some of the recent research has thrown some lights on it. There is a great role of Toll like receptor 4 (TLR-4) for the pathogenesis. These receptors identify the pathogen (The bacterial cell wall lipo- polysaccharides-LPS) and stimulate the host to react to it, induce a pro infla... view more»

Abstract PDF

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