Rodger Loutzenhiser Author

Research Article Open Access

Application of the Reservoir Wave Approach to the Renal Circulation

Author(s):

Kristen C Handkamer, Lindsay M Burrowes , J Christopher Bouwmeester, Ryan Richardet , Rodger Loutzenhiser, and John V Tyberg

 Application of the Reservoir Wave Approach to the Renal Circulation

In this pilot study of the renal circulation we applied the reservoirwave approach, a time-domain method for the analysis of arterial pressure and flow that defines the magnitudes of the series resistances that account for the total vascular resistance of an organ. Renal and systemic pressures and flows were measured in anesthetized dogs. Unilateral infusions of angiotensin II (ANG II) or endothelin-1 (ET-1) decreased renal conductance by 30% and 50%, respectively. These decreases in conductance were acc... view more»

DOI: 10.4172/2324-8602.1000214

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