Sachidanand Peteru Author

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Bupropion with Linezolid: A Review

Author(s):

Divya Periasamy and Sachidanand Peteru

Introduction: Linezolid (Zyvox) is an antibiotic, which belongs to the class of oxazolidinone. FDA approved it in 1998 to treat gram-positive drug-resistant enterococcus, staphylococcus, and pneumococcus infections in adults (MRSA and VRE). Bupropion (Welbutrin) is a medication primarily used as an antidepressant and smoking cessation aid. FDA first approved it in 1985. Both these medications are well known for causing serotonin syndrome when combined with serotonergic agents or administered along with tyramine-rich foods. Case: A 50-year old male patient was admitted to the hospital with right leg cellulitis and was treated with linezolid. The patient also had a history of depression and anxiety and was stable on bupropion for the past two years. Our C... view more»

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