International Journal of Ophthalmic PathologyISSN: 2324-8599

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Sara Gonzalez-Godinez Author


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Amantadine Corneal Toxicity:Case Report and Review of the Literature

Author(s):

Alejandro Rodriguez-Garcia, Sara Gonzalez-Godinez and Yolanda Macias-Rodriguez

Purpose: To report a case of bilateral corneal edema in a patient with a history of cocaine abuse and bipolar-depression treated with amantadine for 6 months, and to review the literature on amantadine corneal toxicity.

Methods: The clinical record of a patient with amantadine corneal toxicity and the existing literature on this subject were extensively reviewed for prevalence, clinical presentation, pathogenesis and therapy.

Results: A 27 year-old male who suffered from depression and cocaine abuse presented with sudden visual loss (20/150 OD and 20/200 OS) caused by bilateral corneal stromal edema without view moreĀ»

DOI: 10.4172/2324-8599.1000165

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