Journal of Virology & Antiviral ResearchISSN: 2324-8955

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Sean (Xuguang) Li Author

sean.li@hc-sc.gc.ca

Subjects of specialization
Gene Therapy, Biotherapeutics, Influenza, SARS-CoV

Affiliation
Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada

Biography

Sean (Xuguang) Li received his medical degree in China, followed by a graduate study and research training in Beijing. He obtained his PhD in experimental medicine from McGill University. As a research fellow, he conducted cancer and virus research at Dana Farber Cancer Institute of Harvard Medical School before he joined the National Microbiology Laboratory in Canada. Currently, Li is a Senior Research Scientist heading the Vaccine Research Laboratory at Health Canada and an Adjunct Professor at the Department of Biochemistry, Microbiology and Immunology.

Publications

Editorial Open Access

Alternative Roles of Neuraminidase in Influenza a Viral Propagation

Author(s):

Tracey M. Doyle and Sean (Xuguang) Li

Alternative Roles of Neuraminidase in Influenza a Viral Propagation

Influenza A is an envelope virus containing a segmented negative RNA genome. The viral envelope has two major surface glycoproteins, Hemagglutinin (HA) and Neuraminidase (NA) of which there are 16 and 9 subtypes respectively. While HA has been well characterized and shown to be essential for viral fusion and entry into host cells, the functional roles of NA in viral replication are much less understood. Some previous reports suggest that NA exerts its primary role during viral exit from the cell by enzymatically cleaving sialic acid and facilitating the release of viral particles from the ... view more»

DOI: 10.4172/2324-8955.1000e104

Abstract HTML PDF

Google Scholars / Researchers Sites

Explore SciTechnol

GET THE APP