International Journal of Cardiovascular ResearchISSN: 2324-8602

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Seyed Hossain Hekmatimoghadamand Marjan Tajik kord Author

mina_poorrajab@yahoo.com +98 351 5231423 | +98 351 5231

Subjects of specialization
Angioplasty,Aortic valve,Arteriosclerosis,Capillaries,Cardiac arrest

Affiliation
Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Publications

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Molecular Strategies Contributing to Efficient Homing of Bone Marrow Stem Cells

Author(s): Fatemeh Pourrajab, Seyed Khalil Forouzannia, Seyed Hossain Hekmatimoghadamand Marjan Tajik kord

Molecular Strategies Contributing to Efficient Homing of Bone Marrow Stem Cells

For successful systemic stem cell therapy, BMSCs must transmigrate across the endothelium and invade their target tissue.A prerequisite for a successful usage of BMSCs is that they exit the blood circulation via transmigration and invasion. The endothelial phenotype selectively modulates BMSCs transmigration and morphological changes. BMSCs exit the blood circulation by integrating into the endothelium, penetrating the basement membrane and invading the surrounding tissue via the formation of plasmic podia.

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DOI: 10.4172/2324-8602.1000102

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