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Hindi Journal of Clinical & Experimental OncologyISSN: 2324-9110
Seyit Ali Gumustas Author
Subjects of specialization
Affiliation
Colorectal cancer, Breast cancer, Facial tumour
Department of Orthopaedic and Traumatology, Dr. Lutfi Kirdar Training and Research Hospital, Istanbul, Turkey
Biography
Seyit Ali Gumustas was working in the Department of Orthopaedic and Traumatology, Dr. Lutfi Kirdar Training and Research Hospital, Istanbul, Turkey. He has more than 40 publications. His current research area related to osteoarthropathy.
Publications
Research Article Open Access
Is it Possible to Expedite Studies on the Effects of Pharmacological Agents on Primary Cell Cultures Obtained from High-grade Fibular Osteosarcoma?
Author(s): Seyit Ali Gumustas, Ibrahim Yilmaz, Mehmet Isyar, Duygu Yasar sirin, Ahmet Guray Batmaz, Aylin Gonultas, Savas Topuk, Olcay Guler, Sibel Kayahan, Semih Akkaya, Önder Ofluoglu and Mahir Mahirogullari
Cell culture and primary cell cultures have been widely used in research in many fields of medicine, particularly cancer research. With the help of cell culture studies, the underlying molecular mechanisms and effects of pharmacological agents have been determined to a great extent. The tumor tissue used for osteosarcoma primary cell culture was obtained from resection surgery carried out in cases with proximal fibula fibroblastic osteosarcoma after three multiagent (neoadjuvant) chemotherapy treatments. The present study not only describes how to prepare human primary osteosarcoma (OS) cell cultures but also encourages and guides orthopedic surgeons in how to set up an in vitro experiment for a drug research.
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