Sharifu LM Author
Subjects of specialization
Affiliation
Obstetrics and Gynecology, HBV Infection, Hepatitis B
Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong, University of Science and Technology, China
Review Article Subscription
Author(s): Sharifu LM, Kibaba P, Jun Y, Yu Z, Jingyi Z, Er-jiao S, Rong L, Shaoshuai W, Ling F
Hepatitis B virus (HBV) is a hepatotropic virus and one of the leading causes by both persistent and chronic infection of hepatitis B in human globally, more over China is a high population was affected by HBV. Currently ETV, TDF, and INF are recommended as a first-line treatment; however, many HBV positive patients will progress to a late stage with diseases such as, chronic hepatitis B cirrhosis and hepatocellular carcinoma (HCC). The uses of pegylated interferon-alpha for 48 weeks have led to a long-term control of HBV, but occasionally treatment failure is observed in a maximum no of patients. Prolonged use of NAs has proofed to suppress the virus, though safety and efficacy is not yet clarified, NAs unable clear the virus from infected cells, suggesting that the disease progression... view moreĀ»