Sokolova K | Author | SciTechnol | Endocrinology & Diabetes Rese

Sokolova K Author

i.goette@yandex.ru +79090195322 | +79090195322

Subjects of specialization
Type 1 diabetes mellitus

Affiliation
Ural Federal University, Ekaterinburg, Russian Federation

Biography

Sokolova K Ural Federal University, Ekaterinburg, Russian Federation. His publications include: 1.International Diabetes Federation (2017) Diabetes Atlas (8th edn). 2.Kharroubi AT, Darwish HM (2015) Diabetes mellitus: The epidemic of the century. World J Diabetes 6: 850–867. 3.Garofolo M, Gualdani E, Giannarelli R, Aragona M, Campi F, et al. (2019) Microvascular complications burden (nephropathy, retinopathy and peripheral polyneuropathy) affects risk of major vascular events and all-cause mortality in type 1 diabetes: a 10-year follow-up study. Cardiovasc Diabetol 18.

Publications

Review Article Open Access

Correction of Biochemical Parameters in Diabetic Rats by Macrophage Activity Modulation

Author(s):

Gette I, Danilova I, Sokolova K and Abidov M

Type 1 and type 2 diabetes mellitus (T1DM and T2DM) are characterized with destructive processes in organs due to hyperglycemia, protein glycation, oxidative stress, gluconeogenesis and lack of anabolic effects of insulin. The violations of various organs are manifested by a change in the biochemical parameters of the blood. Since macrophages are capable of regulating both autoimmune reactions and the process of regeneration of damaged tissues, the use of a macrophage modulator sodium 3-aminophthalhydrazide (SA) could be a promising method for correction the organ damage. The aim of the work is to reveal the possibility of SA to correct plasma parameters of the organ damage in diabetic rats. Fifty male Wistar rats weighing 240-250 g were used in accordance with the Directive 2010/63/EU.... view more»

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