Tamer Demir Author

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Interleukin-11: A Novel Agent in Retinal Ischemia-Reperfusion Injury

Author(s):

Tamer Demir, Azat Alinak, Ahmet Godekmerdan, Burak Turgut and Nesrin Demir

Objective: To investigate the protective effect of recombinant human IL-11 (rhIL-11) administered in a systemic manner on retina tissue during ischemia/reperfusion (I/R) injury in a guinea pig model.

Materials and Methods: An experimental study in retinal I/R. Placebo, ischemia/sham, ischemia/rhIL-11 groups including five animals in each were formed from male albino guinea pigs. Retinal ischemia was induced by cannulating the anterior chambers and lifting the bottle to a height of 205 cm for 90 Min in the ... view more»

DOI: 10.4172/2324-8599.1000104

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