Terence Kin-Wah Lee Author
Subjects of specialization
Affiliation
Gastroenterology, Hepatology, Stem Cells
Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Editorial Open Access
Author(s): Terence Kin-Wah Lee and Nicole Pui-Yu Ho
In recent years, cancer immunotherapy has been a recent hot topic among scientists over the world. So far, the discovered checkpoint protein molecules include cytotoxic T lymphocyte antigen-4 (CTLA-4), programmed death-1 (PD-1), lymphocyte activation gene-3 (LAG-3) and several others. The overexpression of the checkpoint proteins could lead the decreased T-cell cytotoxicity, proliferation and cytokine production.
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