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Hindi Journal of Immunological Techniques & Infectious Diseases ISSN: 2329-9541
Thalhofer CJ Author
Subjects of specialization
Affiliation
Leishmania ; Neutrophils; Flow cytometry
Agonox Inc., Portland, OR 97213
Biography
Dr. Thalhofer CJ was an assistant professor of Agonox Inc., Portland, OR 97213 and later he started his career in Infection and Activation of Human Neutrophils with Fluorescent Leishmania infantum
Publications
Research Article Open Access
Infection and Activation of Human Neutrophils with Fluorescent Leishmania infantum
Author(s): Davis RE, Thalhofer CJ and Wilson ME
Infection and Activation of Human Neutrophils with Fluorescent Leishmania infantum
Neutrophils (PMNs) are recruited in high numbers to sites of host infection by the protozoan parasites of the genus Leishmania. Although PMNs are capable of phagocytizing Leishmania parasites and are potent producers of antimicrobial compounds including reactive oxygen species (ROS), they are unable to control the establishment of infection. Prior studies document production of ROS in isolated PMNs incubated with Leishmania under conditions allowing phagocytosis, however without a measure of single cells’ responses it cannot be discerned whether PMN activation and ROS production is suppressed or i... view more»
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