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Hindi Cell Biology: Research & TherapyISSN: 2324-9293
Todd Evans Author
Subjects of specialization
Affiliation
Surgery,Medical Sciences,Cell Tissue Studies,Cell Regeneration,Cell therapy
Department of Surgery, Weill Cornell Medical College, USA
Biography
Todd Evans is currently working in Department of Surgery, Weill Cornell Medical College, USA. He has international experience on various programs, and also contributed and participated in different countries for diverse fields of study. Research interests reflect in wide range of publications in various national and international journals.
Publications
Special Issue Article Subscription
Control of Epigenetic Memory and Pluripotency by DNA Methylation
Author(s): Ritu Kumar and Todd Evans
Control of Epigenetic Memory and Pluripotency by DNA Methylation
The DNA sequence of most differentiated cells is the same, so that epigenetic mechanisms must provide the means for cells to remember their fate, and maintain a stable and restricted phenotype. DNA methylation is a reversible epigenetic modification that provides one of the major strategies to mark genes to generate cellular memory. In vertebrates, most methyl marks are applied to the 5-position of cytidine at CpG residues, and the role of de novo and maintenance methyltransferases in generating memory is well understood. Less clear has been how methyl marks can be removed, to erase memory and allow cell fat... view more»
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