Journal of Clinical & Experimental OncologyISSN: 2324-9110

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Toshihisa Ogawa Author

rinbara1127@gmail.com

Subjects of specialization
Mucoepidermoid carcinoma, Cancer chemotherapy, Prostate biomarker, Endometrial cancer

Affiliation
Breast Center, Dokkyo Medical University Koshigaya Hospital, 2-1-50 Minamikoshigaya, Koshigaya-Shi, Saitama-ken, Japan

Biography

Toshihisa Ogawa was working in the Breast Center, Dokkyo Medical University Koshigaya Hospital, 2-1-50 Minamikoshigaya, Koshigaya-Shi, Saitama-ken, Japan. He has more than 40 publications. His current research area related to osteoarthropathy. 

Publications

Case Report Open Access

Parathyroid Carcinoma Coincident With Neurofibromatosis Type 1

Author(s):

Noriaki Hayashibara , Toshihisa Ogawa, Eiichi Tsuji, Mariko Oya and Akiko Fujii

Neurofibromatosis type 1 is a genetic disorder resulting from a mutation in the NF1 gene, and is known to have an association with hyperparathyroidism that is caused by parathyroid adenoma in almost all cases. Parathyroid carcinoma in neurofibromatosis type 1 is extremely rare. Among the reports of neurofibromatosis type 1 with comorbid hyperparathyroidism have been a patient with coincident pheochromocytoma and medullary thyroid cancer, and a patient with a mutation of the RET gene, the causative gene of multiple endocrine neoplasia (MEN). These cases suggest an association between neurofibromatosis type 1 and multiple endocrine tumors, but the detailed mechanism is still unknown. Moreover, a mutation in the HRPT2 gene has been noted as a genetic cause of p... view more»

DOI: 10.4172/2324-9110.1000170

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