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Hindi International Journal of Cardiovascular ResearchISSN: 2324-8602
Tumabiene KD Author
Subjects of specialization
Affiliation
heart failure, pulmonary arterial hypertension
Department of Cardiology, UP-Philippine General Hospital, Pasay City, Philippines
Biography
Development of new forms of intervention to improve overall cardiac performance for heart failure remains to be a continuing challenge. Majority of patients with left ventricular dysfunction are dependent on pulmonary vascular resistance and right ventricular performance, parameters that are also important determinants of exercise and functional capacity. Sildenafil, a selective 5-phosphodiesterase inhibitor, is a proven effective therapy for primary and secondary pulmonary arterial hypertension. We conducted this meta-analysis to investigate the role of Sildenafil in lowering pulmonary arterial pressure and improving exercise capacity among patients with systolic heart failure complicated by pulmonary hypertension.
Publications
Research Article Subscription
Sildenafil Improves Exercise Capacity in Heart Failure: A Meta-Analysis (SIC Heart Study)
Author(s): Matulac MO, Macapugay LFP, Reyes MJT, Tumabiene KD, and Mondragon A
Sildenafil Improves Exercise Capacity in Heart Failure: A Meta-Analysis (SIC Heart Study)
Background: Development of new forms of intervention to improve overall cardiac performance for heart failure remains to be a continuing challenge. Majority of patients with left ventricular dysfunction are dependent on pulmonary vascular resistance and right ventricular performance, parameters that are also important determinants of exercise and functional capacity. Sildenafil, a selective 5-phosphodiesterase inhibitor, is a proven effective therapy for primary and secondary view more»
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