Vignaud Jean-Michel Author

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Combination of Daily Low Dose Cisplatin with Thoracic Radiation in Locally Non-Small Cell Lung Cancer for Fragile Patients: An Experimental Monocentric Serie

Author(s):

Clément-Duchêne Christelle*, Salleron Julia, Baumann Anne-Sophie, Royer Philippe, Faivre Jean-Christophe, Ménard Olivier,Vignaud Jean-Michel, Prévot Michel, Peiffert Didier and Beckendorf Véronique

Lung cancer incidence in the elderly is rising over year. The standard treatment for locally non-small cell lung cancer (NSCLC) is based on a combination of chemotherapy and thoracic radiation. No standard is described or validated for patients older than 70 years.

The objective of this retrospective study was to evaluate the toxicities and the feasibility of daily cisplatin at a dose of 6 mg/m² during thoracic irradiation (66-70 Gray) in NSCLC with poor WHO performance status, and/or comorbidities. The second objective was to obtain a first estimation of survival for patients with stage III-IV.

Between 2011 and 2015, 13 patients were retrieved from the hospital database. The medi... view more»

DOI: 10.4172/2324-9110.1000224

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