Vinu Sarathy Author

Research Article Open Access

Association of Epstein-Barr Virus (EBV) Infection with Histomorphological and Immunohistochemical Features of Hodgkin Lymphoma

Author(s):

MVA Sireesha, Rajesh Kumar Ks, Kiran PK, Vinu Sarathy,Suhail Sayeed Mufti, Diganta Hazarika and RadheshyamNaik

Background: Lymphomas are a heterogenous group of lymphoproliferative disorders arising from B-cells, T-cells or Natural Killer (NK) cells, which are classified into Hodgkin and Non-Hodgkin Lymphoma. Hodgkin Lymphoma is categorised into Classical Hodgkin Lymphoma (CHL) and Non Classical types according to clinical, histomorphological, phenotypic and genotypic features. In India, the incidence of lymphoma has increased in the last decade and the increased incidence is found in patients of fifth and sixth decade. The etiology of HL remains unclear, usually arises denovo or seen to arise from Epstein-Barr viral infection. Analyzing expression of abundant EBV small nuclear RNA transcripts (EBER) in RS cells by RNA In Situ Hybridis... view more»

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