Wagenhuser MU Author
Subjects of specialization
Affiliation
Pancreatic cancer,Pancreatic carcinoma,Pancreatic neoplasms,Cell line,Cell therapy
Department of Vascular and Endovascular Surgery
Wagenhäuser MU is a Assistant doctor in the Department of Vascular and Endovascular Surgery, University Hospital Düsseldorf, Germany. Distribution of Characteristic Mutations in Native Ductal Adenocarcinoma of the Pancreas and Pancreatic Cancer Cell Lines
Research Article Open Access
Author(s): Wagenhuser MU, Rockert F, Niedergethmann M, Grotzmann R, and Saeger HD
Distribution of Characteristic Mutations in Native Ductal Adenocarcinoma of the Pancreas and Pancreatic Cancer Cell Lines
Although oncological treatment of pancreatic adenocarcinoma (PDAC) has improved within the last few years, PDAC continues to have a very low 5- year survival rate. Basic research is needed to improve and develop new therapeutic strategies. Pancreatic tumour cell lines (CLs) are a prerequisite for such basic research. However, the isolation of CLs is challenging. Outgrowth of cells is only achieved in a small proportion of tumour samples, although the reason for this poor growth remains unknown.
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