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Hindi Journal of Immunological Techniques & Infectious Diseases ISSN: 2329-9541
Wilson ME Author
Subjects of specialization
Affiliation
Leishmania ; Neutrophils; Flow cytometry
Departments of Internal Medicine and Microbiology, University of Iowa, Iowa City, IA, USA
Biography
Dr. Wilson ME was an assistant professor of Departments of Internal Medicine and Microbiology, University of Iowa, Iowa City, IA, USA and later he started his work on Infection and Activation of Human Neutrophils with Fluorescent Leishmania infantum
Publications
Research Article Open Access
Infection and Activation of Human Neutrophils with Fluorescent Leishmania infantum
Author(s): Davis RE, Thalhofer CJ and Wilson ME
Infection and Activation of Human Neutrophils with Fluorescent Leishmania infantum
Neutrophils (PMNs) are recruited in high numbers to sites of host infection by the protozoan parasites of the genus Leishmania. Although PMNs are capable of phagocytizing Leishmania parasites and are potent producers of antimicrobial compounds including reactive oxygen species (ROS), they are unable to control the establishment of infection. Prior studies document production of ROS in isolated PMNs incubated with Leishmania under conditions allowing phagocytosis, however without a measure of single cells’ responses it cannot be discerned whether PMN activation and ROS production is suppressed or i... view more»
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