Xiaoxia Ma | Author | SciTechnol | Endocrinology & Diabetes Rese

Xiaoxia Ma Author

xiaoxiama@gmail.com

Subjects of specialization
Environmental , Protection

Affiliation
Agro-Environmental Protection Institute, Child and Family Research Institute, UBC, University of Maryland at College Park, beijing University

Biography

Hamamatsu Ika Daigaku, The Jikei University Hospital, Tokyo Dental College Ichikawa General Hospital, University of Western States, Wake Forest University
Alfred Wegener Institute for Polar and Marine Research, Alfred-Wegener-Institut Helmholtz-Zentrum für Polar- und Meeresforschung, Institute of Deep-Sea Science and

Publications

Short Communication Open Access

Metformin Influences Bile Acids to Improve the Glucose and Lipid Metabolism in Rats with Streptozotocin-induced Type 2 Diabetes Mellitus

Author(s):

Jianting Li, Yang Liu, Qiang Jiang, Lulu Wang, Rui Shi, Xiaoxia Ma, Lin Ding and Shuguang Pang

The prevalence of type 2 diabetes mellitus (T2DM), which is characterized by an increased blood glucose concentration, insulin resistance and pancreatic beta-cell dysfunction has reached epidemic proportions worldwide and represents an important threat to global public health systems [1]. On the basis of available clinical evidence, metformin has been affirmed as the first-line therapy for patients with T2DM [2]. Although a few pathophysiological mechanisms have been proposed to explain these beneficial clinical effects of metformin, detailed mechanisms of action of metformin are still not fully understood, especially its relationship with bile acids.

DOI: 10.4172/2470-7570.1000124

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