Yang S Author
Subjects of specialization
Affiliation
General Pediatrics, Neonatology, ,Adolescent Medicine,Pediatri Critical Care, ,Development Pediatrics and Neuropsychology,
Associate Professor of Management Science and Operations
He has working and consulting experience in companies, financial institutions, and international organizations. He is currently collaborating with companies in the area of supply chain finance, FinTech, and business analytics.
Review Article Open Access
Author(s): Yang S, So TY
Pulmonary hypertension can be diagnosed at all ages and characterized by increased vascular resistance in the lungs. Pulmonary hypertension in the pediatric population is less studied than in adults with much of the therapy extrapolated from adult data. Suboptimal survival rate of patients with pulmonary hypertension and the economic impact this disease has on the healthcare system warrant the need for new therapeutic options, such as citrulline. Citrulline is a non-essential amino acid involved in the urea cycle, which ultimately converts to nitric oxide to help dilate the pulmonary vasculature. Based on the available animal and few human studies, citrulline can potentially be a preventive remedy for pediatric patients at high risk of developing pulmonary hypertension after undergoing ... view moreĀ»