Yongguang Zhang Author

Research Article Open Access

The Influence of Porcine Reproductive and Respiratory Syndrome Virus Infection on the Expression of Cellular Prion Protein in Marc-145 Cells

Author(s):

Chongxu Shi, Yaozhong Ding, Xiaoyuan Ma, Yali Liu, Yunwen Ou, Bing Ma, Alexei D Zaberezhny, Zygmunt Pejsak, Anna Szczotka-Bochniarz, Yongguang Zhang and Jie Zhang

Cellular prion protein (PrPC) represents a potential regulator of cellular immunity and has been confirmed to be an invasive receptor exploited by bacteria such as Brucella abortus to facilitate the infection in host cells. Up to now, there are few informations about the role of PrPC in virus replication in host cells. Porcine reproductive and respiratory syndrome virus (PRRSV), a single positive-stranded RNA virus, prefers to infect African green monkey kidney cell line MA-104 and its der... view more»

DOI: 10.4172/2324-8955.1000146

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