Cell Biology: Research & TherapyISSN: 2324-9293

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Research Article, Cell Biol Res Ther Vol: 3 Issue: 1

Ck AE1/AE3 Tumor Marker Expression in SCC of Head and Neck

Nauman Rauf Khan1*, Amna Nauman Khan2, Ejaz Waris3, Bilquis A. Suleman4 and Ayyaz Ali Khan5
1Oral Pathology, Sharif Medical & Dental College, Pakistan
2Community Dentistry, Sharif Medical & Dental College, Pakistan
3Department of Histopathology, Akhtar Saeed Medical & Dental College, Pakistan
4Department of Histopathology, University of Lahore, Pakistan
5Department of Oral Health Sciences, Shaikh Zayed Post Graduate Medical Complex, Pakistan
Corresponding author : Dr. Nauman Rauf Khan
Oral Pathology, Sharif Medical & Dental College, 397-Q, Model Town, Lahore, Pakistan
E-mail: [email protected]
Received: January 01, 2014 Accepted: March 10, 2014 Published: March 13, 2014
Citation: Khan NR, Khan AN, Waris E, Suleman BA, Khan AA (2014) Ck AE1/AE3 Tumor Marker Expression in SCC of Head and Neck. Cell Biol: Res Ther 3:1. doi:10.4172/2324-9293.1000109


Immunostaining is one of the latest and accurate modality for evaluating the diagnosis and prognosis of tumors. It has also become a very important tool of differentiating between the tumors of different origin. Aims of the present study were to assess the frequency, pattern, sensitivity and specificity of CytokeratinAE1/AE3 as an immunohistochemical marker for the Squamous Cell Carcinomas(SCC) of head and neck.

Keywords: Squamous cell carcinoma; Immunostaining; Cytokeratin AE1/AE3; Head and neck cancer; Genotoxic stress; Oligomerization

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