Analgesia & Resuscitation : Current ResearchISSN: 2324-903X

Reach Us +1 850 754 6199
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Research Article, Analg Resusc Curr Res S Vol: 2 Issue: 0

Comparing Resuscitative Measures for Bupivacaine Toxicity Utilizing Lipid Emulsions in a swine model(Sus scrofa)

Andrea Hudson1, Sarah Bolin2, Mark Bishop3, Randall Schmidt4, Arthur D Johnson5 and Joseph O’Sullivan5*
1Landstuhl Regional Medical Center, Landstuhl, Germany
2Madigan Army Medical Center, Tacoma, Washington, USA
3Ireland Army Community Hospital, FT Knox, Kentucky, USA
4Dwight D Eisenhower Army Medical Center, FT Gordon, Georgia, USA
5Army Medical Department Center and School, San Antonio, Texas, USA
Corresponding author : Joseph O’Sullivan
3490 Forage Rd, Dunlap Hall, Ft Sam Houston, TX 78234
Tel: 210-295-4769
E-mail: [email protected]
Received: May 13, 2013 Accepted: July 01, 2013 Published: July 08, 2013
Citation: Hudson A, Bolin S, Bishop M, Schmidt R, Johnson AD, et al. (2013) Comparing Resuscitative Measures for Bupivacaine Toxicity Utilizing Lipid Emulsions in a swine model (Sus scrofa). Analg Resusc: Curr Res S1. doi:10.4172/2324-903X.S1-006

Abstract

Comparing Resuscitative Measures for Bupivacaine Toxicity Utilizing Lipid Emulsions in a swine model(Sus scrofa)

A toxic dose of bupivacaine causes cardiac arrhythmias and ultimately asystole. Resuscitation is difficult and almost always unsuccessful. Until recently, cardiopulmonary bypass was the only effective treatment. Anecdotal evidence suggests that infusion of lipid emulsion may be an effective treatment. No studies have determined the optimal combination of lipid rescue and traditional Advanced Cardiac Life Support (ACLS) therapy for a toxic dose of bupivacaine. The purpose was to determine the optimal combination of lipid rescue and traditional ACLS therapy for treatment overdose of bupivacaine.

 

Keywords: Bupivacaine

Track Your Manuscript

Share This Page