International Journal of Ophthalmic PathologyISSN: 2324-8599

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Research Article, Int J Ophthalmic Pathol Vol: 2 Issue: 3

Comparison of Topical 0.03% Tacrolimus in Almond and Linseed Oil to Treat Experimentally Induced Keratoconjunctivitis Sicca in Rabbits

Marcos Rogerio Sgrignoli1, Letícia Yamasaki2, Osimar de Carvalho Sanches2, Rogério Giuffrida3, Claudia Lizandra Ricci3, Gabriela de Campos Santos3, Heloisa Ferreira Duarte do Valle3, Luis Felipe da Costa Zulim3, Daniele Alves Silva4, Karina Maria Basso4, Mariele Catherine Alves Silva4 and Silvia Franco Andrade5*
1University of Oeste Paulista (UNOESTE), Brazil
2Department of Anatomy Pathology (UNOESTE), Brazil
3Faculty of Veterinary Medicine (UNOESTE), Brazil
4Resident of the Veterinary Hospital (UNOESTE), Brazil
5Department of Small Animal Medicine of the Veterinary Hospital (UNOESTE), Brazil
Corresponding author: Silvia Franco Andrade
Department of Small Animal Medicine of the Veterinary Hospital (UNOESTE), Rodovia Raposos Tavares, Km 572, CEP 19001-970, Presidente Prudente, SP, Brazil
Tel: +5518 32292067; Fax: +5518 32292036
E-mail: [email protected]
Received: March 02, 2013 Accepted: April 10, 2013 Published: April 18, 2013
Citation: Sgrignoli MR, Yamasaki L, de Carvalho Sanches O, Giuffrida R, Ricci CL, et al. (2013) Comparison of Topical 0.03% Tacrolimus in Almond and Linseed Oil to Treat Experimentally Induced Keratoconjunctivitis Sicca in Rabbits. Int J Ophthalmic Pathol 2:3. doi:10.4172/2324-8599.1000114

Abstract

Keratoconjunctivitis sicca (KCS), or dry eye syndrome, is a common inflammatory disease of the ocular surface in animals and humans that is characterized by quantitative and/or qualitative tear change. The quantitative alterations are due to an aqueous component deficiency, and the qualitative alterations are due to a lipid or mucin layer deficiency that results in the instability of the pre-corneal tear film.

Keywords: Almond oil; Keratoconjunctivitis sicca; Linseed oil, Rabbits, Tacrolimus, Topical treatment

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