Analgesia & Resuscitation : Current ResearchISSN: 2324-903X

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Research Article, Analg Resusc Curr Res S Vol: 2 Issue: 0

The Effects Vasopressin and Epinephrine on Cardiac Arrest Following Desipramine Overdose in a Porcine Model

Don Johnson*, Joseph O’Sullivan, Allan Bolido, Jennifer Brady, Brian Gallahan, Ken Gore, Tammy King, Heather Leal, Brian Lowery, Kyle Stevens
US Army Graduate Program in Anesthesia, Fort Sam Houston, Texas
Corresponding author : Don Johnson
Building 1394, 3490 Forage Road, Fort Sam Houston, 78234
Tel: 210-849-7364
E-mail: [email protected]
Received: June 06, 2013 Accepted: July 24, 2013 Published: July 29, 2013
Citation: Johnson D, O’Sullivan J, Bolido A, Brady J, Gallahan B, et al. (2013) The Effects Vasopressin and Epinephrine on Cardiac Arrest Following Desipramine Overdose in a Porcine Model Analg Resusc: Curr Res S1. doi:10.4172/2324-903X.S1-012

Abstract

The Effects Vasopressin and Epinephrine on Cardiac Arrest Following Desipramine Overdose in a Porcine Model

Desipramine, a tricyclic antidepressant, is used for depression particularly related to post traumatic stress disorder. The use of the drug escalates the possibility of an overdose. The purpose of this study was to determine the survivability of swine that have a cardiac arrest from an overdose of desipramine. This was the first study to investigate the effects of vasopressin vs. epinephrine in the treatment of cardiac arrest following an overdose of desipramine.

Keywords: Vasopressin; Epinephrine; Desipramine; Porcine model

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