Journal of Clinical & Experimental OncologyISSN: 2324-9110

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Research Article, J Clin Exp Oncol Vol: 2 Issue: 4

Encapsulated Minimally Invasive Epimyoepithelial Carcinoma of Submandibular Gland - A New Entity?? With Review of Literature

Shelly Arora1*, Aadithya B Urs1 and Nita Khurana2
1Department of Oral and Maxillofacial Pathology, Maulana Azad Institute of Dental Sciences , Bahadur Shah Zafar Marg, NewDelhi,India
2Department of General Pathology, Maulana Azad Medical College, Bahadur Shah Zafar Marg, New Delhi, India
Corresponding author : Shelly Arora
Senior Research Associate, Department of Oral and Maxillofacial Pathology, Maulana Azad Institute of Dental Sciences , Bahadur Shah Zafar Marg, NewDelhi-110002, India
Tel: 91-8800168368; Fax: 011-2321708
E-mail: [email protected]
Received: August 22, 2013 Accepted: December 13, 2013 Published: December 22, 2013
Citation: Shelly A, Aadithya BU, Nita K (2013) Encapsulated Minimally Invasive Epimyoepithelial Carcinoma of Submandibular Gland - A New Entity?? With Review of Literature. J Clin Exp Oncol 2:4. doi:10.4172/2324-9110.1000116

Abstract

Encapsulated Minimally Invasive Epimyoepithelial Carcinoma of Submandibular Gland - A New Entity?? With Review of Literature

Epimyoepithelial carcinoma (EMC) is a rare low-grade salivary gland malignancy comprising of 1% of all the salivary glands tumors. EMC is a rare tumor when involving submandibular gland (8.6%) as compared to parotid gland (62.1%). A thorough pubmed literature search retrieved only 17 cases of EMC involving submandibular gland since 1972. EMC can present in classical pattern characterised by biphasic cell population with inner layer of cuboidal to columnar cells and outer layer of myoepithelial cells. Encapsulated minimally invasive epimyoepithelial carcinoma is a recently coined terminology by Seethala et al. To the best of our knowledge, this is the first case of encapsulated minimally invasive EMC of submandibular salivary gland discussed in the literature. The present paper highlights the review of literature of EMC involving submandibular salivary gland, histomorphological spectrum and diagnostic differentiation from other salivary gland tumors.

Keywords: Cellular pleomorphic adenoma; Epimyoepithelial carcinoma; Histomorphology; Myoepithelial cell; Salivary gland tumor

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