Journal of Liver: Disease & TransplantationISSN: 2325-9612

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Editorial, J Liver Dis Transplant Vol: 4 Issue: 2

Endoplasmic Reticulum Stress in Drug-Induced Liver Injury and Liver Diseases: An Unlighted Novel Mechanism

Erkekoglu P*, Koçer-Gümü�?�?el B, Elnour A and Bhagavathula AS
Department of Toxicology, Hacettepe University, 06100, Ankara, Turkey
Corresponding author : Pinar Erkekoglu
Faculty of Pharmacy, Department of Toxicology, Hacettepe University, 06100, Ankara, Turkey
Tel: +90 312 305 21 78; Fax: +90 312 311 47 77
E-mail: erkekp@yahoo.com
Received: October 06, 2015 Accepted: October 08, 2015 Published: October 12, 2015
Citation: Erkekoglu P, Koçer-Gümüsel B, Elnour A, Bhagavathula AS (2015) Endoplasmic Reticulum Stress in Drug-Induced Liver Injury and Liver Diseases: An Unlighted Novel Mechanism. J Liver: Dis Transplant 4:2. doi:10.4172/2325-9612.1000e109

Abstract

The endoplasmic reticulum (ER) is a very important organelle in the eukaryotic cells. It has two types: rough endoplasmic reticulum (rough ER, RER) and smooth endoplasmic reticulum (smooth ER, SER). ER plays a vital role in many cellular processes such as secretory and membrane protein synthesis, folding, assembly, trafficking and post-modulation. The lumen of the ER contains the highest concentration of Ca2+ within the cell because of active transport of calcium ions by Ca2+ ATPases and it is a unique environment in which an incredible process of protein quality control checking is performed.

Keywords: Liver Injury; Endoplasmic Reticulum

international publisher, scitechnol, subscription journals, subscription, international, publisher, science

Track Your Manuscript

Awards Nomination

open access