Journal of Molecular Medicine & Therapeutics#

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Research Article, Mol Med Ther Vol: 1 Issue: 2

Genome-Scale Mapping of MicroRNA Signatures in Human Embryonic Stem Cell Neurogenesis

Xuejun H. Parsons1,2*, James F. Parsons1,2 and Dennis A. Moore1,2
1San Diego Regenerative Medicine Institute, San Diego, CA 92109, USA
2Xcelthera, San Diego, CA 92109, USA
Corresponding author : Dr. Xuejun H. Parsons
San Diego Regenerative Medicine Institute, San Diego, CA 92109, USA
E-mail: [email protected]
Received: September 18, 2012 Accepted: November 20, 2012 Published: December 10, 2012
Citation: Parsons XH, Parsons JF, Moore1 DA (2012) Genome-Scale Mapping of MicroRNA Signatures in Human Embryonic Stem Cell Neurogenesis. Mol Med Ther 1:2. doi:10.4172/2324-8769.1000105

Abstract

Genome-Scale Mapping of MicroRNA Signatures in Human Embryonic Stem Cell Neurogenesis

To date, lacking of a clinically-suitable source of engraftable human stem/progenitor cells with adequate neurogenic potential has been the major setback in developing effective cell-based therapies against a wide range of neurological disorders. Derivation of human embryonic stem cells (hESCs) provides a powerful tool to investigate the molecular controls in human embryonic neurogenesis as well as an unlimited source to generate the diversity of human neuronal cell types in the developing CNS for repair.

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